For 25 years on her hit talk show, Oprah Winfrey shared valuable wisdom to inspire personal growth and help others navigate their bumpy lives.

But where did Winfrey turn for her own self-help?

"I've never been to a therapist because I had so many on the show, but my real therapy came from downloading whatever was happening in the day with Gayle every night," she tells PEOPLE in an interview for the magazine’s 50th anniversary special issue.